View bacteriocin : Enterocin A

 Bookmark and Share

Accession BAC088
Name Enterocin A
Related Entries Enterocin QEnterocin PEnterocin I (Enterocin L50A)Enterocin BEnterocin 1071A

Enterocin CRL35 (Mundticin KS)Enterocin SE-K4Enterocin AS-48 (BACTERIOCIN AS-48)Enterocin 96Enterocin E-760

Enterocin-HFEnterocin XalphaEnterocin XbetaEnterocin EJ97
Gene entA
Class Class IIa, IIc (problematic)
Producer Organism Enterococcus faecium (Streptococcus faecium) [Gram-positive]
Taxonomy BacteriaFirmicutesLactobacillalesEnterococcaceaeEnterococcus
Target organisms Enterococcus faecalis JCM 5803 (MIC=64.7nM) - Enterococcus faecalis OU510 (MIC=32.3nM) - Enterococcus faecium JCM 5804 (MIC=200nM) - Enterococcus faecium TUA 1344L (MIC=129nM) - Enterococcus hirae ATCC 10541 (MIC=129nM) - Lactobacillus plantarum ATCC 14917 (MIC=259nM) - Lactobacillus sakei ssp. sakei JCM 1157 (MIC=16.2nM) - Lactococcus lactis ssp. cremoris ATCC 19257 (MIC=4140nM) - Bacillus coagulans JCM 2257 (MIC=8280nM) - Bacillus subtilis JCM 1465 (MIC=4140nM) - Listeria innocua ATCC 33090 (MIC=1040nM) - Enterococcus - Lactobacillus - Pediococcus - Listeria monocytogenes
Swiss-Prot Entry Q47784
PDB Entry Unknown
Other databases EMBL X94181EMBL AB038464EMBL AF099088HSSP P34034GO GO:0005576

GO GO:0042742InterPro IPR002633Pfam PF01721ProDom PD004452
[Ref. 1] | View abstract | Export citation
NUCLEOTIDE SEQUENCE, STRAIN=CTC492
MEDLINE=96209231;PubMed=8633865;
Aymerich T., Holo H., Havarstein L.S., Hugas M., Garriga M., Nes I.F.
"Biochemical and genetic characterization of enterocin A from Enterococcus faecium, a new antilisterial bacteriocin in the pediocin family of bacteriocins.", Appl. Environ. Microbiol. 62:1676-1682(1996).

[Ref. 2]
NUCLEOTIDE SEQUENCE, STRAIN=CTC492
Harvarstein L.
"", Submitted (DEC-1995) to the EMBL/GenBank/DDBJ databases.

[Ref. 3]
NUCLEOTIDE SEQUENCE, STRAIN=N15
Uchiyama K., Losteinkit C., Shioya S.
"Characterization of bacteriocin produced by Enterococcus faecium N15 and cloning of the related genes.", Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases.

[Ref. 4] | View abstract | Export citation
NUCLEOTIDE SEQUENCE, STRAIN=DPC1146
MEDLINE=99203104;PubMed=10103244;
O'Keeffe T., Hill C., Ross R.P.
"Characterization and heterologous expression of the genes encoding enterocin A production, immunity, and regulation in Enterococcus faecium DPC1146.", Appl. Environ. Microbiol. 65:1506-1515(1999).

[Ref. 5] | View abstract | Export citation
NUCLEOTIDE SEQUENCE, STRAIN=KU-B5.
PubMed=20418437;DOI=10.1128/AEM.02264-09
Hu C.-B., Malaphan W., Zendo T., Nakayama J., Sonomoto K.
"Enterocin X, a novel two-peptide bacteriocin from Enterococcus faecium KU-B5, has an antibacterial spectrum entirely different from those of its component peptides.", Appl. Environ. Microbiol. 76:4542-4545(2010).

Loading...
End Note
Reference Manager
BibTeX
Sequence
 ........10 ........20 ........30 ........40 ........50 
          |          |          |          |          | 
 TTHSGKYYGN GVYCTKNKCT VDWAKATTCI AGMSIGGFLG GAIPGKC
Wheel representation
Composition
Formula C211 H329 N57 O63 S5
Absent amino acids EQR
Common amino acids G
Mass (Da) 4851.38
Net charge +5
Isoelectric point 8.98
Basic residues 6
Acidic residues 1
Hydrophobic residues 12
Polar residues 26
Aliphatic residues 6
Tiny residues 15
Boman Index -20.81
Hydropathy Index -0.03
Aliphatic Index 54.04
Instability Index 25.08 (stable)
Half Life Mammalian : 7.2 hour
Yeast : >20 hour
E. coli : >10 hour
Extinction Coefficient 10220 M-1 cm-1
Absorbance 280nm 222.17
Red solid plot : values according to the hydrophobicity scale of Kyte and Doolittle (reference paper).


Yellow dashed plot : Experimentally determined hydrophobicity scale for proteins at membrane interfaces(reference paper).


Green dotted-dashed plot : prediction of transmembrane helices (reference paper). In this scale (unlike the others), more negative values reflect greater hydrophobicity.

Users comments for Enterocin A

No comments found

Login or register to submit a comment for Enterocin A.