View bacteriocin : Enterocin 1071A

General data
References
Structural data
Physicochemical data
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Accession	BAC106
Name	Enterocin 1071A
Related Entries	Enterocin Q Enterocin P Enterocin I (Enterocin L50A)Enterocin A Enterocin B Enterocin CRL35 (Mundticin KS)Enterocin SE-K4 Enterocin AS-48 (BACTERIOCIN AS-48)Enterocin 96 Enterocin E-760 Enterocin-HF Enterocin Xalpha Enterocin Xbeta Enterocin EJ97
Gene	ent1071A
Class	~~Unclassified~~
Producer Organism	Enterococcus faecalis (Streptococcus faecalis) [Gram-positive]
Taxonomy	BacteriaFirmicutesLactobacillalesEnterococcaceaeEnterococcus
Target organisms	~~Unavailable data~~
Swiss-Prot Entry	Q9L9U6
PDB Entry	~~Unknown~~
Other databases	*EMBL* AF164559 *InterPro* IPR012950 *Pfam* PF08129

[Ref. 1] | View abstract | Export citation

NUCLEOTIDE SEQUENCE, STRAIN=BFE 1071
MEDLINE=20208822;PubMed=10742203;DOI=10.1128/AEM.66.4.1298-1304.2000
Balla E., Dicks L.M., Du Toit M., Van Der Merwe M.J., Holzapfel W.H.
"Characterization and cloning of the genes encoding enterocin 1071A and enterocin 1071B, two antimicrobial peptides produced by Enterococcus faecalis BFE 1071.", Appl. Environ. Microbiol. 66:1298-1304(2000).

[Ref. 2] | View abstract | Export citation

NUCLEOTIDE SEQUENCE, STRAIN=BFE 1071
PubMed=15718027;DOI=10.1016/j.ijfoodmicro.2004.08.008
Balla E., Dicks L.M.
"Molecular analysis of the gene cluster involved in the production and secretion of enterocins 1071A and 1071B and of the genes responsible for the replication and transfer of plasmid pEF1071.", Int. J. Food Microbiol. 99:33-45(2005).

Sequence

........10 ........20 ........30 ........40 ........50 ........60
| | | | | |
MKQYKVLNEK EMKKPIGGES VFSKIGNAVG PAAYWILKGL GNMSDVNQAD RINRKKH

Wheel representation

Composition

Formula	C₂₈₃ H₄₆₂ N₈₂ O₈₀ S₃
Absent amino acids	CT
Common amino acids	K
Mass (Da)	6408.42
Net charge	+7
Isoelectric point	10.6
Basic residues	12
Acidic residues	5
Hydrophobic residues	17

Polar residues	16
Aliphatic residues	11
Tiny residues	13
Boman Index	-101.24
Hydropathy Index	-0.68
Aliphatic Index	75.26
Instability Index	13.64 (stable)
Half Life	Mammalian : 30 hour Yeast : >20 hour E. coli : >10 hour
Extinction Coefficient	8480 M^-1 cm^-1
Absorbance 280nm	151.43

Red solid plot : values according to the hydrophobicity scale of Kyte and Doolittle (reference paper).

Yellow dashed plot : Experimentally determined hydrophobicity scale for proteins at membrane interfaces(reference paper).

Green dotted-dashed plot : prediction of transmembrane helices (reference paper). In this scale (unlike the others), more negative values reflect greater hydrophobicity.

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