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View bacteriocin : Enterocin E-760 |
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| [Ref. 1] | View abstract | Export citation | [1]PROTEIN SEQUENCE, FUNCTION, BIOPHYSICOCHEMICAL PROPERTIES, SUBCELLULARLOCATION, AND MASS SPECTROMETRY.STRAIN=NRRL B-30745 PubMed=18086839;DOI=10.1128/AAC.01569-06 Line J.E., Svetoch E.A., Eruslanov B.V., Perelygin V.V., Mitsevich E.V., Mitsevich I.P., Levchuk V.P., Svetoch O.E., Seal B., Siragusa G., Stern N.J. "Isolation and purification of enterocin E-760 with broad antimicrobial activity against Gram-positive and Gram-negative bacteria.", Antimicrob. Agents Chemother. 52:1094-1100(2008) |
| Sequence |
........10 ........20 ........30 ........40 ........50 ........60 ........70 | | | | | | | NRWYCNSAAG GVGGAAVCGL AGYVGEAKEN IAGEVRKGWG MAGGFTHNKA CKSFPGSGWA SG |
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| Wheel representation |
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| Formula |
C269
H403
N81
O80
S4
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| Absent amino acids |
DQ |
| Common amino acids |
G |
| Mass (Da) |
6198.95 |
| Net charge |
+4 |
| Isoelectric point |
8.91 |
| Basic residues |
7 |
| Acidic residues |
3 |
| Hydrophobic residues |
21 |
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| Polar residues |
29 |
| Aliphatic residues |
6 |
| Tiny residues |
29 |
| Boman Index |
-42.8 |
| Hydropathy Index |
-0.18 |
| Aliphatic Index |
47.42 |
| Instability Index |
42.56 (unstable)
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| Half Life |
Mammalian : 1.4 hour
Yeast : 3 min
E. coli : >10 hour |
| Extinction Coefficient |
19480 M-1 cm-1 |
| Absorbance 280nm |
321.39 |
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Red solid plot : values according to the hydrophobicity scale of Kyte and Doolittle (reference paper).
Yellow dashed plot : Experimentally determined hydrophobicity scale for proteins at membrane interfaces(reference paper).
Green dotted-dashed plot : prediction of transmembrane helices (reference paper). In this scale (unlike the others), more negative values reflect greater hydrophobicity.
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