View bacteriocin : Microcin-24

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Accession BAC176
Name Microcin-24
Related Entries Microcin J25microcin B17 (MccB17)Microcin H47Microcin E492Colicin-V (Microcin-V)

Microcin C7
Gene mtfS
Class Unclassified
Producer Organism Escherichia coli [Gram-negative]
Taxonomy BacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Target organisms Unavailable data
Swiss-Prot Entry Q46971
PDB Entry Unknown
Other databases EMBL U47048TCDB 1.C.58.1.2GO GO:0005102GO GO:0019835GO GO:0042742
Description Channel-forming bacteriocin
[Ref. 1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].STRAIN=2424;
O'Brien G.J., Mahanty H.K.
"Complete nucleotide sequence of microcin 24 genetic region andanalysis of a new ABC transporter.", Submitted (JAN-1996) to the EMBL/GenBank/DDBJ database

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Sequence
 ........10 ........20 ........30 ........40 ........50 ........60 ........70 ........80 
          |          |          |          |          |          |          |          | 
 AGDPLADPNS QIVRQIMSNA AWGPPLVPER FRGMAVGAAG GVTQTVLQGA AAHMPVNVPI PKVPMGPSWN GSKG
Wheel representation
Composition
Formula C332 H529 N97 O95 S4
Absent amino acids CY
Common amino acids AGP
Mass (Da) 7546.94
Net charge +3
Isoelectric point 10.76
Basic residues 6
Acidic residues 3
Hydrophobic residues 27
Polar residues 20
Aliphatic residues 14
Tiny residues 24
Boman Index -45.85
Hydropathy Index -0.03
Aliphatic Index 76.49
Instability Index 36.99 (stable)
Half Life Mammalian : 30 hour
Yeast : >20 hour
E. coli : >10 hour
Extinction Coefficient 11000 M-1 cm-1
Absorbance 280nm 150.68
Red solid plot : values according to the hydrophobicity scale of Kyte and Doolittle (reference paper).


Yellow dashed plot : Experimentally determined hydrophobicity scale for proteins at membrane interfaces(reference paper).


Green dotted-dashed plot : prediction of transmembrane helices (reference paper). In this scale (unlike the others), more negative values reflect greater hydrophobicity.

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