View bacteriocin : serracin-P Bookmark and Share

Accession BAC002
Name serracin-P
Gene Unidentified
Class Unclassified
Producer Organism Serratia plymuthica [Gram-negative]
Taxonomy BacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSerratia
Target organisms Gram-negative: Erwinia amylovora
Swiss-Prot Entry P83375
PDB Entry Unknown
Description Mode of action:
Major component of a prophage tail sheath (Probable).
[Ref. 1] | View abstract | Export citation
PROTEIN SEQUENCE, AND FUNCTION, STRAIN=J7
MEDLINE=22293561;PubMed=12406768;
Jabrane A., Sabri A., Compere P., Jacques P., Vandenberghe I., Van Beeumen J., Thonart P.
"Characterization of serracin P, a phage-tail-like bacteriocin, and its activity against Erwinia amylovora, the fire blight pathogen.", Appl. Environ. Microbiol. 68:5704-5710(2002).

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Sequence
........10
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DYHHGVRVL

Warning: N-terminal amino acid sequence of the 43-kDa serracin P subunit.
Wheel representation
Composition
AA N° %

AA N° %

AA N° %
Ala 0 .00%

Ile 0 .00%

Arg 1 11.11%
Cys 0 .00%

Lys 0 .00%

Ser 0 .00%
Asp 1 11.11%

Leu 1 11.11%

Thr 0 .00%
Glu 0 .00%

Met 0 .00%

Val 2 22.22%
Phe 0 .00%

Asn 0 .00%

Trp 0 .00%
Gly 1 11.11%

Pro 0 .00%

Tyr 1 11.11%
His 2 22.22%

Gln 0 .00%
Total 9
Formula C49 H74 N16 O13
Absent amino acids ACEFIKMNPQSTW
Common amino acids HV
Mass (Da) 1113.37
Net charge +2
Isoelectric point 7.71
Basic residues 3
Acidic residues 1
Hydrophobic residues 3
Polar residues 2
Aliphatic residues 3
Tiny residues 1
Boman Index -19.16
Hydropathy Index -0.43
Aliphatic Index 107.78
Instability Index 11.08 (stable)
Half Life Mammalian : 1.1 hour
Yeast : 3 min
E. coli : >10 hour
Extinction Coefficient 1490 M-1 cm-1
Absorbance 280nm 186.25
Red solid plot : values according to the hydrophobicity scale of Kyte and Doolittle (reference paper).


Yellow dashed plot : Experimentally determined hydrophobicity scale for proteins at membrane interfaces(reference paper).


Green dotted-dashed plot : prediction of transmembrane helices (reference paper). In this scale (unlike the others), more negative values reflect greater hydrophobicity.

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